BPC-157 VIP Combo

Description

BPC-157 VIP Peptide Combo

Combining BPC-157 and VIP peptides presents a comprehensive approach to promoting gut health and overall well-being. BPC-157’s renowned gastrointestinal protective effects, promoting tissue repair and reducing inflammation, can complement VIP’s role in regulating intestinal functions and supporting digestive system health.

The synergistic action of these peptides may contribute to improved gut integrity, enhanced gut motility, and a balanced gut microbiome. This peptide combination offers a promising strategy for addressing gastrointestinal issues, promoting optimal digestive function, and supporting overall gut wellness.

What is BPC-157 Peptide?

BPC-157 peptide, also known as a penta-decapeptide, contains 15 amino acids. It is a component of the body protection compound (BPC) discovered in and isolated from human stomach juice. This peptide can help repair a variety of wounds in animals, including muscle and tendon injury and torn ligaments, by speeding up the healing process. [1]

Furthermore, BPC 157 has been demonstrated to preserve organs and prevent stomach ulcers, which can be excruciatingly painful. BPC-157 has been shown in research to alleviate leaky gut, IBS, intestinal cramps, and Crohn’s disease by acting on many pathways in the digestive tract. Furthermore, Japan studies have indicated that this peptide can assist reduce pain.

Evidence suggests that BPC-157 can speed up the healing process of skin burns by improving blood flow to the affected areas. In wound healing, BPC-157 accelerates reticulin and collagen production, as well as angiogenesis and macrophage and fibroblast infiltration. [2]

What is VIP Peptide?

Vasoactive Intestinal Peptide (VIP) is a neuropeptide that plays a crucial role in regulating various physiological functions within the body. This peptide, consisting of 28 amino acids, is widely distributed in the nervous system and acts as a neurotransmitter, neuromodulator, and vasodilator. VIP exerts its effects by binding to specific G-protein coupled receptors, notably VPAC1 and VPAC2 receptors, which are present in various tissues including the brain, gastrointestinal tract, and immune system [3].

VIP is known for its diverse functions, including the regulation of circadian rhythms, neurotransmission, immune responses, and gastrointestinal motility. In the gut, VIP influences smooth muscle relaxation, secretion of digestive enzymes, and maintenance of gut barrier integrity. Additionally, VIP has anti-inflammatory properties and can modulate immune cell activity, highlighting its role in immune regulation. Japan Research suggests that VIP may also have neuroprotective effects and be involved in pain modulation [4].

The multifaceted actions of VIP make it a promising target for therapeutic applications in various conditions, such as gastrointestinal disorders, inflammatory diseases, and neurological conditions. Further Japan research into VIP’s mechanisms of action and potential clinical benefits continues to expand our understanding of this important neuropeptide.

Specifications:

BPC-157

Sequence: H-Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val-OH

Molecular Formula: C62H98N16O22

Molecular Weight: 1419.5 g/mol

Size: 2mg

VIP

Sequence: HSDAVFTDNYXRLRKQM AVKKYLNSXLN

Molecular Formula: C147H237N43043S

Size: 2mg

Physical Appearance: White Lyophilised Solid
Form: Sterile Filtered White Lyophilized
Solubility: Water Soluble

Benefits for Researchers:

The BPC-157 VIP Combo holds considerable promise for Japan research professionals due to the following benefits:

• Gut Health: Together, the BPC-157 VIP peptides may enhance gut integrity, improve gut motility, and contribute to a balanced gut microbiome. The collaborative action of BPC-157 and VIP peptides can potentially address gastrointestinal issues comprehensively, promote optimal digestive function, and support overall gut wellness.
• Anti-inflammatory Properties: When used together, BPC-157 and VIP peptides can synergistically combat inflammation. BPC-157 is recognized for its anti-inflammatory properties that aid in tissue repair and inflammation reduction, while VIP acts as a potent anti-inflammatory agent, modulating immune responses. The combined action of these peptides can lead to a more comprehensive approach in reducing inflammation throughout the body. By leveraging the anti-inflammatory effects of both BPC-157 and VIP, this peptide combination shows promise in addressing inflammatory conditions, promoting tissue healing, and supporting overall wellness.
• Tissue repair and Wound healing: Combining BPC-157 VIP peptides can synergistically promote tissue repair due to their individual abilities. BPC-157 is known for stimulating tissue regeneration and accelerating wound healing processes by promoting collagen production and reducing inflammation. On the other hand, VIP peptide plays a role in supporting tissue repair and healing through its anti-inflammatory properties and modulation of immune responses. Together, these peptides can enhance the repair mechanisms within the body, potentially speeding up recovery from injuries and improving tendon-to-bone healing.

References:

[1] Huang T, Zhang K, Sun L, Xue X, Zhang C, Shu Z, Mu N, Gu J, Zhang W, Wang Y, Zhang Y, Zhang W. Body protective compound-157 enhances alkali-burn wound healing in vivo and promotes proliferation, migration, and angiogenesis in vitro. Drug Des Devel Ther. 2015 Apr 30;9:2485-99.

[2] Chang CH, Tsai WC, Hsu YH, Pang JH. Pentadecapeptide BPC 157 enhances the growth hormone receptor expression in tendon fibroblasts. Molecules. 2014 Nov 19;19(11):19066-77.

[3] Tan YV, Couvineau A, Laburthe M. Diffuse pharmacophoric domains of vasoactive intestinal peptide (VIP) and further insights into the interaction of VIP with the N-terminal ectodomain of human VPAC1 receptor by photoaffinity labeling with [Bpa6]-VIP. J Biol Chem. 2004 Sep 10;279(37):38889-94.

[4] Waschek JA. VIP and PACAP: neuropeptide modulators of CNS inflammation, injury, and repair. Br J Pharmacol. 2013 Jun;169(3):512-23.

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